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Special Collection: Ultrafast Contrast Imaging
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- Original Contribution
High Frame Rate Contrast-Enhanced Ultrasound Imaging for Slow Lymphatic Flow: Influence of Ultrasound Pressure and Flow Rate on Bubble Disruption and Image Persistence
Ultrasound in Medicine and BiologyVol. 45Issue 9p2456–2470Published online: July 3, 2019- Jiaqi Zhu
- Shengtao Lin
- Chee Hau Leow
- Ethan M. Rowland
- Kai Riemer
- Sevan Harput
- and others
Cited in Scopus: 5Contrast-enhanced ultrasound (CEUS) utilising microbubbles shows great potential for visualising lymphatic vessels and identifying sentinel lymph nodes (SLNs) which are valuable for axillary staging in breast cancer patients. However, current CEUS imaging techniques have limitations that affect the accurate visualisation and tracking of lymphatic vessels and SLN. (i) Tissue artefacts and bubble disruption can reduce the image contrast. (ii) Limited spatial and temporal resolution diminishes the amount of information that can be captured by CEUS.