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    • Original Contribution
      Open Access

      Microbubble Void Imaging: A Non-invasive Technique for Flow Visualisation and Quantification of Mixing in Large Vessels Using Plane Wave Ultrasound and Controlled Microbubble Contrast Agent Destruction

      Ultrasound in Medicine and Biology
      Vol. 41Issue 11p2926–2937Published online: August 18, 2015
      • Chee Hau Leow
      • Francesco Iori
      • Richard Corbett
      • Neill Duncan
      • Colin Caro
      • Peter Vincent
      • and others
      Cited in Scopus: 11
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        There is increasing recognition of the influence of the flow field on the physiology of blood vessels and their development of pathology. Preliminary work is reported on a novel non-invasive technique, microbubble void imaging, which is based on ultrasound and controlled destruction of microbubble contrast agents, permitting flow visualisation and quantification of flow-induced mixing in large vessels. The generation of microbubble voids can be controlled both spatially and temporally using ultrasound parameters within the safety limits.
        Microbubble Void Imaging: A Non-invasive Technique for Flow Visualisation and Quantification of Mixing in Large Vessels Using Plane Wave Ultrasound and Controlled Microbubble Contrast Agent Destruction
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