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    • Cover Image - Ultrasound in Medicine and Biology, Volume 49, Issue 4
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  • Original Contribution
    Open Access

    Flow Velocity Mapping Using Contrast Enhanced High-Frame-Rate Plane Wave Ultrasound and Image Tracking: Methods and Initial in Vitro and in Vivo Evaluation

    Ultrasound in Medicine and Biology
    Vol. 41Issue 11p2913–2925Published online: August 12, 2015
    • Chee Hau Leow
    • Eleni Bazigou
    • Robert J. Eckersley
    • Alfred C.H. Yu
    • Peter D. Weinberg
    • Meng-Xing Tang
    Cited in Scopus: 80
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    Ultrasound imaging is the most widely used method for visualising and quantifying blood flow in medical practice, but existing techniques have various limitations in terms of imaging sensitivity, field of view, flow angle dependence, and imaging depth. In this study, we developed an ultrasound imaging velocimetry approach capable of visualising and quantifying dynamic flow, by combining high-frame-rate plane wave ultrasound imaging, microbubble contrast agents, pulse inversion contrast imaging and speckle image tracking algorithms.
    Flow Velocity Mapping Using Contrast Enhanced High-Frame-Rate Plane Wave Ultrasound and Image Tracking: Methods and Initial in Vitro and in Vivo Evaluation
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