Abstract
The reproducibility of volume measurements in intravascular ultrasound (IVUS) images
derived from separate pull-back manoeuvres remains to be elucidated. Patients (n = 23) were imaged with IVUS prior to (first series) and following percutaneous transluminal
angioplasty (PTA) (second series). In 15 patients, one matched vascular segment (3–4
cm in length), not subjected to PTA, was used for analysis of lumen, vessel and plaque
volume using an automated contour analysis system. Volume measurements assessed by
two independent observers and in the two separate series were compared. Interobserver
differences in volume measurements were small (≤ 0.4%), with low coefficients of variation
(≤ 1.7%) and high correlation coefficients (r = 1.00). Differences in volume measurements obtained in the two separate series were
small (≤ 2.6%), with low coefficients of variation (≤ 8.6%) and high correlation coefficients
(r = 0.97–0.99). In conclusion, volume measurements derived from IVUS images are highly
reproducible. Therefore, IVUS may be used to monitor the progression/regression of
atherosclerotic plaque volume in a longitudinal study.
Keywords
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Article info
Publication history
Accepted:
September 13,
1999
Received:
June 2,
1999
Identification
Copyright
© 2000 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.