Abstract
Motion extracted from the carotid artery wall provides unique information for vascular
health evaluation. Carotid artery longitudinal wall motion corresponds to the multiphasic
arterial wall excursion in the direction parallel to blood flow during the cardiac
cycle. While this motion phenomenon has been well characterized, there is a general
lack of awareness regarding its implications for vascular health assessment or even
basic vascular physiology. In the last decade, novel estimation strategies and clinical
investigations have greatly advanced our understanding of the bi-axial behavior of
the carotid artery, necessitating an up-to-date review to summarize and classify the
published literature in collaboration with technical and clinical experts in the field.
Within this review, the state-of-the-art methodologies for carotid wall motion estimation
are described, and the observed relationships between longitudinal motion-derived
indices and vascular health are reported. The vast number of studies describing the
longitudinal motion pattern in plaque-free arteries, with its putative application
to cardiovascular disease prediction, point to the need for characterizing the added
value and applicability of longitudinal motion beyond established biomarkers. To this
aim, the main purpose of this review was to provide a strong base of theoretical knowledge,
together with a curated set of practical guidelines and recommendations for longitudinal
motion estimation in patients, to foster future discoveries in the field, toward the
integration of longitudinal motion in basic science as well as clinical practice.
Key Words
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Article info
Publication history
Published online: July 21, 2020
Accepted:
June 7,
2020
Received in revised form:
June 1,
2020
Received:
December 10,
2019
Identification
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