Abstract
To investigate the effects of fluid resuscitation on cerebral hemodynamics in sepsis,
the following set of transcranial Doppler (TCD) parameters was used: maximal change
in flow velocity (FV) during stroke onset (acc), maximal FV during first (sys1) or
second (sys2) phase of systole and mean diastolic FV ([email protected]). We aim to evaluate
changes in cerebral hemodynamics that result from (i) sepsis and (ii) adequate fluid
resuscitation in critically ill septic patients. In the majority of 16 septic patients
sys2 was initially absent but reappeared during the period of fluid resuscitation;
whereas sys2 absence was never seen in healthy controls. Second, adequate fluid resuscitation
resulted in a significant increase of the systolic FV components (acc, sys1, sys2
and systolic blood pressure); whereas the diastolic components ([email protected] and diastolic
blood pressure) remained unchanged. Sys2 absence and reappearance in sepsis suggests
that TCD could become a non-invasive alternative for hemodynamic monitoring.
Key Words
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Article info
Publication history
Published online: August 02, 2017
Accepted:
June 23,
2017
Received in revised form:
June 16,
2017
Received:
March 7,
2017
Identification
Copyright
© 2017 World Federation for Ultrasound in Medicine & Biology Printed in the USA. All rights reserved.
