Ultrasound in Medicine and Biology
Volume 38, Issue 2 , Pages 183-189, February 2012

Evaluation of Color Doppler Ultrasonography in Diagnosing Hepatic Alveolar Echinococcosis

  • Song Tao

      Affiliations

    • Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
    • Xinjiang Key Lab of Fundamental Medical Research and Xinjiang Hydatid Clinical Research Institute, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Zhao Qin

      Affiliations

    • Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Li Haitao

      Affiliations

    • Xinjiang Key Lab of Fundamental Medical Research and Xinjiang Hydatid Clinical Research Institute, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Yang Lei

      Affiliations

    • Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Yao Lanhui

      Affiliations

    • Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Xu Qin

      Affiliations

    • Consulting Office of Medical Statistics, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Lu Yongquan

      Affiliations

    • Department of Ultrasonography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
  • ,
  • Wen Hao

      Affiliations

    • Xinjiang Key Lab of Fundamental Medical Research and Xinjiang Hydatid Clinical Research Institute, First Affiliated Hospital, Xinjiang Medical University, Urumqi, PR China
    • Corresponding Author InformationAddress correspondence to: Wen Hao, Xinjiang Key Lab of Fundamental Medical Research and Xinjiang Hydatid Clinical Research Institute, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830000, PR China.

Received 18 September 2011; received in revised form 2 November 2011; accepted 17 November 2011.

Abstract 

To assess the accuracy of color Doppler ultrasonography in diagnosing hepatic alveolar echinococcosis, 129 patients were examined at the First Affiliated Hospital of Xinjiang Medical University between July 2004 and June 2010. Those patients suspected of having hepatic alveolar echinococcosis were examined and diagnosed by color Doppler ultrasound. All the cases were compared with the gold standard. The findings of their sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio and 95% confidence interval were recorded. Sensitivity: 95% (95% confidence interval: 90.7%–99.3%); specificity: 20.7% (95% confidence interval: 6.0%–35.4%); positive predictive value: 80.5%; negative predictive value: 54.5%; positive likelihood ratio: 1.2: negative likelihood ratio: 0.2. Our study indicates that color Doppler ultrasonography, when used in diagnosing hepatic alveolar echinococcosis, has high sensitivity although specificity is low. Color Doppler ultrasound is, thus, considered to be an efficient means for diagnosing hepatic alveolar echinococcosis.

Key Words: Color Doppler, Ultrasonography, Hepatic alveolar echinococcosis

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PII: S0301-5629(11)01487-6

doi:10.1016/j.ultrasmedbio.2011.11.010

Ultrasound in Medicine and Biology
Volume 38, Issue 2 , Pages 183-189, February 2012