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Ultrasound in Medicine and Biology
Volume 36, Issue 2
, Pages 181-191
, February 2010
Critical Appraisal of Targeted Ultrasound Contrast Agents for Molecular Imaging in Large Arteries
References
- . Development of inherently echogenic liposomes as an ultrasonic contrast agent. J Pharm Sci. 1996;85:486–490
- . Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow. Nature. 1995;374:539–542
- . A contrast-enhanced ultrasound study of benign and malignant breast tissue. S Afr Med J. 2008;98:386–391
- . Functional imaging of inflammatory diseases using nuclear medicine techniques. Semin Nucl Med. 2009;39:124–145
- . Cellular and molecular imaging with targeted contrast ultrasound. Ultrasound Q. 2006;22:67–72
- . Steady flow in a model of the human carotid bifurcation. Part I-Flow visualization. J Biomech. 1982;15:349–362
- . Steady flow in a model of the human carotid bifurcation. Part II-Laser-Doppler anemometer measurements. J Biomech. 1982;15:363–378
- . Diagnostic efficacy of SonoVue. Am J Cardiol. 2000;86:19G–24G
- . Vascular flow and perfusion imaging with ultrasound contrast agents. Ultrasound Med Biol. 2004;30:735–743
- . Chemoattractants induce a rapid and transient upregulation of monocyte alpha4 integrin affinity for vascular cell adhesion molecule 1 which mediates arrest: An early step in the process of emigration. J Exp Med. 2001;193:1149–1158
- . Targeted therapeutic applications of acoustically active microspheres in the microcirculation. Microcirculation. 2006;13:57–70
- . Large variations in absolute wall shear stress levels within one species and between species. Atherosclerosis. 2007;195:225–235
- . Physical and biochemical characterization of Albunex, a new ultrasound contrast agent consisting of air-filled albumin microspheres suspended in a solution of human albumin. Biotechnol Appl Biochem. 1994;19(Pt 3):307–320
- . Improved left ventricular endocardial border delineation and opacification with OPTISON (FS069), a new echocardiographic contrast agent. Results of a phase III Multicenter Trial. J Am Coll Cardiol. 1998;32:746–752
- . Investigating perfluorohexane particles with high-frequency ultrasound. Ultrasound Med Biol. 2006;32:73–82
- . A model for reflectivity enhancement due to surface bound submicrometer particles. Ultrasound Med Biol. 2006;32:1247–1255
- . Model for the ultrasound reflection from micro-beads and cells distributed in layers on a uniform surface. Phys Med Biol. 2007;52:4189–4204
- . Sonic activation of molecularly-targeted nanoparticles accelerates transmembrane lipid delivery to cancer cells through contact-mediated mechanisms: Implications for enhanced local drug delivery. Ultrasound Med Biol. 2005;31:1693–1700
- . Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc Natl Acad Sci U S A. 2004;101:14871–14876
- . Molecular ultrasound imaging using microbubble contrast agents. Front Biosci. 2007;12:5124–5142
- . Basic acoustic properties of microbubbles. Echocardiography. 2002;19:229–240
- . Principles and recent developments in ultrasound contrast agents. Ultrasonics. 1991;29:324–330
- . In vivo targeting of acoustically reflective liposomes for intravascular and transvascular ultrasonic enhancement. J Am Coll Cardiol. 1999;33:867–875
- . In vitro targeting of acoustically reflective immunoliposomes to fibrin under various flow conditions. J Drug Target. 1998;5:507–518
- . In vitro targeting of antibody-conjugated echogenic liposomes for site-specific ultrasonic image enhancement. J Pharm Sci. 1997;86:167–171
- . Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs. Biophys J. 2003;85:2720–2731
- . Identification of ultrasound echoes from the left ventricle by use of intracardiac injections of indocyanine green. Circulation. 1970;41:615–621
- . Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization. J Am Coll Cardiol. 2006;48:236–243
- . Pharmacokinetics and side effects of perfluorocarbon-based blood substitutes. Artif Cells Blood Substit Immobil Biotechnol. 1994;22:1043–1054
- . Aging mechanisms of perfluorocarbon emulsions using image analysis. J Colloid Interface Sci. 2005;286:224–232
- . Shear-dependent thickening of the human arterial intima. Atherosclerosis. 1986;60:161–171
- . Adhesion of monocytes to vascular cell adhesion molecule-1-transduced human endothelial cells: Implications for atherogenesis. Circ Res. 1998;82:871–878
- . Endothelial dysfunction, hemodynamic forces, and atherogenesis. Ann N Y Acad Sci. 2000;902:230–239discussion 239–240
- . Echocardiography of the aortic root. Invest Radiol. 1968;3:356–366
- . Allometric scaling of wall shear stress from mice to humans: Quantification using cine phase-contrast MRI and computational fluid dynamics. Am J Physiol Heart Circ Physiol. 2006;291:H1700–1708
- . Time evolution of enhanced ultrasonic reflection using a fibrin-targeted nanoparticulate contrast agent. J Acoust Soc Am. 2000;108:3049–3057
- . Left ventricular thrombus enhancement after intravenous injection of echogenic immunoliposomes: Studies in a new experimental model. Circulation. 2002;105:2772–2778
- . A physiologic flow chamber model to define intravascular ultrasound enhancement of fibrin using echogenic liposomes. Invest Radiol. 2002;37:215–221
- . Intravascular ultrasound molecular imaging of atheroma components in vivo. J Am Coll Cardiol. 2004;43:453–460
- . Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352:1685–1695
- . Physical correlates of the ultrasonic reflectivity of lipid dispersions suitable as diagnostic contrast agents. Ultrasound Med Biol. 2002;28:339–348
- . Acoustically active liposomes for drug encapsulation and ultrasound-triggered release. Biochim Biophys Acta. 2004;1665:134–141
- . Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circ Res. 2000;87:153–159
- . Relation between air-filled albumin microbubble and red blood cell rheology in the human myocardium. Influence of echocardiographic systems and chest wall attenuation. Circulation. 1996;94:445–451
- . Molecular imaging of cardiovascular disease. Circulation. 2007;116:1052–1061
- . In vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography. Comparison with radiolabeled red blood cells. Circ Res. 1994;74:1157–1165
- . Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1. Circulation. 2007;116:276–284
- . Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle. J Control Release. 2007;118:275–284
- . Lipid contribution to the affinity of antigen association with specific antibodies conjugated to liposomes. Biochim Biophys Acta. 2007;1768:1703–1716
- . Targeting of ultrasound contrast material. An in vitro feasibility study. Acta Radiol Suppl. 1997;412:113–120
- . Targeting and ultrasound imaging of microbubble-based contrast agents. Magma. 1999;8:177–184
- . Targeting of ultrasound contrast material: Selective imaging of microbubbles in vitro. Acad Radiol. 1998;5(Suppl.1):S243–S246
- . Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett. 1990;268:235–237
- . Detection of individual microbubbles of ultrasound contrast agents: Imaging of free-floating and targeted bubbles. Invest Radiol. 2004;39:187–195
- . Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media Mol Imaging. 2006;1:259–266
- . Perfluorohexane-loaded macrophages as a novel ultrasound contrast agent: A feasibility study. Mol Imaging Biol. 2008;10:264–270
- . Effect of microbubble ligation to cells on ultrasound signal enhancement: Implications for targeted imaging. Invest Radiol. 2006;41:721–728
- . Molecular imaging of stretch-induced tissue factor expression in carotid arteries with intravascular ultrasound. Invest Radiol. 2000;35:227–234
- . In vitro characterization of a novel, tissue-targeted ultrasonic contrast system with acoustic microscopy. J Acoust Soc Am. 1998;104:3665–3672
- . High-frequency ultrasonic detection of thrombi with a targeted contrast system. Ultrasound Med Biol. 1997;23:863–870
- . A novel site-targeted ultrasonic contrast agent with broad biomedical application. Circulation. 1996;94:3334–3340
- . Targeted ultrasonic contrast agents for molecular imaging and therapy. Curr Probl Cardiol. 2003;28:625–653
- . Improved imaging of infections by avidin-induced clearance of 99mTc-biotin-PEG liposomes. J Nucl Med. 2000;41:912–918
- . Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L, P, E). J Cell Biol. 1997;136:717–727
- . Getting to the site of inflammation: The leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7:678–689
- . Assessment of inflammation with contrast ultrasound. Prog Cardiovasc Dis. 2001;44:111–120
- . Detection of inflamed plaques with contrast ultrasound. Am J Cardiol. 2002;90:32L–35L
- . Molecular imaging with contrast ultrasound and targeted microbubbles. J Nucl Cardiol. 2004;11:215–221
- . Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes. Circulation. 2000;101:668–675
- . Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation. 2000;102:531–538
- . Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation. 2001;104:2107–2112
- . Microvascular rheology of Definity microbubbles after intra-arterial and intravenous administration. J Am Soc Echocardiogr. 2002;15:396–403
- . Characterisation of biotinylated liposomes for in vivo targeting applications. FEBS Lett. 1993;332:183–188
- . Atherosclerosis. Nature. 2000;407:233–241
- . Improvements in the ultrasonic contrast of targeted perfluorocarbon nanoparticles using an acoustic transmission line model. IEEE Trans Ultrason Ferroelectr Freq Control. 2002;49:29–38
- . Temperature dependence of acoustic impedance for specific fluorocarbon liquids. J Acoust Soc Am. 2002;112:2858–2862
- . Molecular imaging with targeted perfluorocarbon nanoparticles: Quantification of the concentration dependence of contrast enhancement for binding to sparse cellular epitopes. Ultrasound Med Biol. 2007;33:950–958
- . Direct observation of catch bonds involving cell-adhesion molecules. Nature. 2003;423:190–193
- . Perfluorocarbon distribution to liver, lung and spleen of emulsions of perfluorotributylamine (FTBA) in pigs and rats and perfluorooctyl bromide (PFOB) in rats and dogs by 19F NMR spectroscopy. Artif Cells Blood Substit Immobil Biotechnol. 1994;22:1243–1250
- . Optimization of spray drying by factorial design for production of hollow microspheres for ultrasound imaging. J Biomed Mater Res. 2001;56:333–341
- . Contrast agents in diagnostic ultrasound. Ultrasound Med Biol. 1989;15:319–333
- . Fluoroalkylated polyethylene glycol as potential surfactant for perfluorocarbon emulsion. Artif Cells Blood Substit Immobil Biotechnol. 2001;29:483–492
- . Relationship between turbidity of lipid vesicle suspensions and particle size. Anal Biochem. 2001;291:158–162
- . Physical principles of microbubble ultrasound contrast agents. Am J Cardiol. 2002;90:3J–7J
- . Wall shear stress—An important determinant of endothelial cell function and structure in the arterial system in vivo. Discrepancies with Theory. J Vasc Res. 2006;43:251–269
- . Flow velocity patterns in and distensibility of the carotid artery bulb in subjects of various ages. Circulation. 1985;71:500–509
- . Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update. Biomed Pharmacother. 2008;62:536–540
- . Unsteady flow in a rigid 3-D model of the carotid artery bifurcation. J Biomech Eng. 1996;118:90–96
- . Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340:115–126
- . Clinical experience with SonoVue in myocardial perfusion imaging. Echocardiography. 2000;17:S17–23
- . Acoustic radiation force enhances targeted delivery of ultrasound contrast microbubbles: In vitro verification. IEEE Trans Ultrason Ferroelectr Freq Control. 2005;52:421–433
- . Enhanced targeting of ultrasound contrast agents using acoustic radiation force. Ultrasound Med Biol. 2007;33:1132–1139
- . Selectin ligands promote ultrasound contrast agent adhesion under shear flow. Mol Pharm. 2006;3:516–524
- . Deformable gas-filled microbubbles targeted to P-selectin. J Control Release. 2006;114:288–299
- . Wall shear stress in the human common carotid artery as function of age and gender. Cardiovasc Res. 1998;39:515–522
- . Doppler enhancement with SH U 508A in multiple vascular regions. Radiology. 1994;193:195–201
- . Particle diameter influences adhesion under flow. Biophys J. 2001;80:1733–1743
- . Further studies on ultrasonic properties of blood clots. J Clin Ultrasound. 1986;14:269–275
- . Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound Med Biol. 2007;33:797–809
- . Phagocytosis of a fluorescently labeled perflubron emulsion by a human monocyte cell line. Artif Cells Blood Substit Immobil Biotechnol. 1994;22:1215–1221
- . Artificial O2 carriers: Status in 2005. Curr Pharm Des. 2005;11:4099–4114
- . Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell. 1994;76:301–314
- . Gene delivery by combination of novel liposomal bubbles with perfluoropropane and ultrasound. J Control Release. 2007;117:130–136
- . Effective gene delivery with novel liposomal bubbles and ultrasonic destruction technology. Int J Pharm. 2008;354:49–55
- . Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow. J Control Release. 2004;96:473–482
- . Labeling monocytes for imaging chronic inflammation. Q J Nucl Med Mol Imaging. 2009;53:78–88
- . Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent. Stroke. 2007;38:2841–2843
- . Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells. Circulation. 1998;98:1–5
- . Albumin microbubble adherence to human coronary endothelium: Implications for assessment of endothelial function using myocardial contrast echocardiography. J Am Coll Cardiol. 1997;30:689–693
- . Modulating targeted adhesion of an ultrasound contrast agent to dysfunctional endothelium. Ann Biomed Eng. 2002;30:1012–1019
- . Targeted ultrasound contrast agents: In vitro assessment of endothelial dysfunction and multitargeting to ICAM-1 and sialyl Lewisx. Biotechnol Bioeng. 2005;92:780–788
- . Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine. Cancer Res. 2005;65:533–539
- . Molecular imaging and therapy of atherosclerosis with targeted nanoparticles. J Magn Reson Imaging. 2007;25:667–680
- . Versatility in lipid compositions showing prolonged circulation with sterically stabilized liposomes. Biochim Biophys Acta. 1992;1105:193–200
- . Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res. 1983;53:502–514
- . Selective imaging of adherent targeted ultrasound contrast agents. Phys Med Biol. 2007;52:2055–2072
PII: S0301-5629(09)01537-3
doi: 10.1016/j.ultrasmedbio.2009.09.009
© 2010 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
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Ultrasound in Medicine and Biology
Volume 36, Issue 2
, Pages 181-191
, February 2010
