Ultrasound in Medicine and Biology
Volume 36, Issue 2 , Pages 268-275 , February 2010

Quantitative Ultrasonic Elastography for Gel Dosimetry

  • Remo A. Crescenti

      Affiliations

    • Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
    • ,
  • Jeffrey C. Bamber

      Affiliations

    • Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
    • Corresponding Author InformationAddress correspondence to: Jeffrey Bamber, Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, SM2 5TP, United Kingdom.
    • ,
  • Assad A. Oberai

      Affiliations

    • Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
    • ,
  • Paul E. Barbone

      Affiliations

    • Department of Mechanical Engineering, Boston University, Boston, MA, USA
    • ,
  • Joseph P. Richter

      Affiliations

    • Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
    • ,
  • Carlos Rivas

      Affiliations

    • Department of Mechanical Engineering, Boston University, Boston, MA, USA
    • ,
  • Nigel L. Bush

      Affiliations

    • Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
    • ,
  • Steve Webb

      Affiliations

    • Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

Received 26 September 2008 ,Revised 28 August 2009 ,Accepted 14 September 2009.

References 

  1. Bamber JC, Bush NL, Trapp J, Partridge M. Backscatter readout of radiation sensitive gels. Ultrasound. 2004;12:230–230
  2. Barbone PE, Bamber JC. Quantitative elasticity imaging: What can and cannot be inferred from strain images. Phys Med Biol. 2002;47:2147–2164
  3. Crescenti RA, Scheib SG, Schneider U, Gianolini S. Introducing gel dosimetry in a clinical environment: Customization of polymer gel composition and magnetic resonance imaging parameters used for 3-D dose verifications in radiosurgery and intensity modulated radiotherapy. Med Phys. 2007;34:1286–1297
  4. Crescenti RA, Bamber JC, Bush NL, Webb S. Characterization of dose-dependent Young's modulus for a radiation-sensitive polymer gel. Phys Med Biol. 2009;54:843–857
  5. De Deene Y, Vergote K, Claeys C, De Wagter C. The fundamental radiation properties of normoxic polymer gel dosimeters: A comparison between a methacrylic acid based gel and acrylamide based gels. Phys Med Biol. 2006;51:653–673
  6. Doyley MM, Meaney PM, Bamber JC. Evaluation of an iterative reconstruction method for quantitative elastography. Phys Med Biol. 2000;45:1521–1540
  7. Fong PM, Keil DC, Does MD, Gore JC. Polymer gels for magnetic resonance imaging of radiation dose distributions at normal room atmosphere. Phys Med Biol. 2001;46:3105–3113
  8. Gore JC, Ranade M, Maryañski MJ, Schulz RJ. Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner. Phys Med Biol. 1996;41:2695–2704
  9. Hilts M, Audet C, Duzenli C, Jirasek A. Polymer gel dosimetry using X-ray computed tomography: a feasibility study. Phys Med Biol. 2000;45:2559–2571
  10. Hughes TJR. The finite element method: Linear static and dynamic finite element analysis. New York: Dover Publications; 2000;
  11. Kallel F, Bertrand M, Ophir J. Fundamental limitations on the contrast-transfer efficiency in elastography: An analytic study. Ultrasound Med Biol. 1996;22:463–470
  12. Mather ML, Baldock C. Ultrasound tomography imaging of radiation dose distributions in polymer gel dosimeters: Preliminary study. Med Phys. 2003;30:2140–2148
  13. Oberai AA, Gokhale NH, Feijóo GR. Solution of inverse problems in elasticity imaging using the adjoint method. Inverse Problems. 2003;19:297–313
  14. Oberai AA, Gokhale NH, Doyley MM, Bamber JC. Evaluation of the adjoint equation based algorithm for elasticity imaging. Phys Med Biol. 2004;49:2955–2974
  15. Ophir J, Céspedes I, Ponnekanti H, Yazdi Y, Li X. Elastography: A quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging. 1991;13:111–134
  16. Trapp JV, SÅJ Bäck, Lepage M, Michael G, Baldock C. An experimental study of the dose response of polymer gel dosimeters imaged with X-ray computed tomography. Phys Med Biol. 2001;46:2939–2951
  17. Vogel CR. Computational methods for inverse problems. Philadelphia: SIAM; 2002;

PII: S0301-5629(09)01530-0

doi: 10.1016/j.ultrasmedbio.2009.09.003

Ultrasound in Medicine and Biology
Volume 36, Issue 2 , Pages 268-275 , February 2010

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