Comparison of Degree of Stenosis and Plaque Volume for the Assessment of Carotid Atherosclerosis Using 2-D Ultrasound

Abstract 

The degree of carotid stenosis (%ST) remains the most frequently used parameter for identifying patients with high risk of stroke but the relationship between %ST and the occurrence of stroke remains controversial. The objectives of this study were to check (1) the relationship between the %ST and the plaque volume index (PVI) as measured by echography and Doppler, (2) the relationship between the intima media thickness (IMT), a vessel wall remodeling index and the PVI an atheromatous growth index. For each of the 128 patients, (165 carotid stenosis), we measured the % ST (section or diameter), the max stenosis velocity (V_max), the PVI and the common carotid IMT. The %ST (section) ranged from 10% to 93% (mean 66±18), V_max from 0.3m/s to 3m/s (mean 1.2±0.8), PVI from 0.61cm³ to 1.17cm³ (mean 0.41±0.21) and the IMT from 0.08cm up to 0.31cm (mean 0.12±0.03). There was no significant correlation between either PVI and %ST (section or diameter), PVI and minimal stenosis section area (S1) or between PVI and V_max. There was no significant correlation between IMT and both %ST area and PVI. PVI was significantly correlated with the whole artery section area (S2) and the plaque length (L). The %ST (section or diameter) was significantly correlated with S1 but not with S2. The absence of correlation between the PVI and the %ST confirm that these two parameters describe two different processes of the atheromatous development. (E-mail: arbeille@med.univ-tours.fr)

Key Words: Carotid, plaque, Volume, Stenosis degree, Echography