Ultrasound in Medicine and Biology
Volume 34, Issue 3 , Pages 400-405 , March 2008

In Vitro Mitral Chordal Cutting by High Intensity Focused Ultrasound

  • Yukio Abe

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • Corresponding Author InformationAddress correspondence to: Yukio Abe, MD, Department of Medicine Cardiology Division, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, PH3-133, New York, NY 10032 USA.
    • ,
  • Ryo Otsuka

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Robert Muratore

      Affiliations

    • Riverside Research Institute, New York, NY, USA
    • ,
  • Kana Fujikura

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Kazue Okajima

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Keiko Suzuki

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Jie Wang

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Charles Marboe

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA
    • ,
  • Andrew Kalisz

      Affiliations

    • Riverside Research Institute, New York, NY, USA
    • ,
  • Jeffrey A. Ketterling

      Affiliations

    • Riverside Research Institute, New York, NY, USA
    • ,
  • Frederic L. Lizzi

      Affiliations

    • Riverside Research Institute, New York, NY, USA
    • ,
  • Shunichi Homma

      Affiliations

    • College of Physicians and Surgeons, Columbia University, New York, NY, USA

Received 28 March 2007 ,Revised 16 July 2007 ,Accepted 5 September 2007.

References 

  1. Barber JE, Kasper FK, Ratliff NB, Cosgrove DM, Griffin BP, Vesely I. Mechanical properties of myxomatous mitral valves. J Thorac Cardiovasc Surg. 2001;122:955–962
  2. Blondheim DS, Jacobs LE, Kotler MN, Costacurta GA, Parry WR. Dilated cardiomyopathy with mitral regurgitation: Decreased survival despite a low frequency of left ventricular thrombus. Am Heart J. 1991;122:763–771
  3. Chen L, ter Haar G, Robertson D, Bensted JP, Hill CR. Histological study of normal and tumor-bearing liver treated with focused ultrasound. Ultrasound Med Biol. 1999;25:847–856
  4. Damianou C. In vitro and in vivo ablation of porcine renal tissues using high-intensity focused ultrasound. Ultrasound Med Biol. 2003;29:1321–1330
  5. Engel DJ, Muratore R, Hirata K, Otsuka R, Fujikura K, Sugioka K, et al. Myocardial lesion formation using high-intensity focused ultrasound. J Am Soc Echocardiogr. 2006;19:932–937
  6. Fayad G, Modine T, Le Tourneau T, Al-Ruzzeh S, Ennezat PV, Decoene C, et al. Chordal cutting technique through aortotomy: A new approach to treat chronic ischemic mitral regurgitation. J Thorac Cardiovasc Surg. 2005;129:1173–1174
  7. Fujikura K, Otsuka R, Kalisz A, Ketterling JA, Jin Z, Sciacca RR, et al. Effects of ultrasonic exposure parameters on myocardial lesions induced by high-intensity focused ultrasound. J Ultrasound Med. 2006;25:1375–1386
  8. Fry WJ, Barnard JW, Fry EJ, Krumins RF, Brennan JF. Ultrasonic lesions in the mammalian central nervous system. Science. 1955;122:517–518
  9. Grigioni F, Enriquez-Sarano M, Zehr KJ, Bailey KR, Tajik AJ. Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler assessment. Circulation. 2001;103:1759–1764
  10. Hickey AJ, Wilcken DE, Wright JS, Warren BA. Primary (spontaneous) chordal rupture: relation to myxomatous valve disease and mitral valve prolapse. J Am Coll Cardiol. 1985;5:1341–1346
  11. Huang SK, Graham AR, Hoyt RH, Odell RC. Transcatheter desiccation of the canine left ventricle using radiofrequency energy: A pilot study. Am Heart J. 1987;114:42–48
  12. Isner JM, Michlewitz H, Clarke RH, Donaldson RF, Konstam MA, Salem DN. Laser-assisted debridement of aortic valve calcium. Am Heart J. 1985;109:448–452
  13. Isner JM, Donaldson RF, Deckelbaum LI, Clarke RH, Laliberte SM, Ucci AA, et al. The excimer laser: Gross, light microscopic and ultrastructural analysis of potential advantages for use in laser therapy of cardiovascular disease. J Am Coll Cardiol. 1985;6:1102–1109
  14. Kolios MC, Sherar MD, Hunt JW. Large blood vessel cooling in heated tissues: a numerical study. Phys Med Biol. 1995;40:477–494
  15. Kolios MC, Sherar MD, Hunt JW. Blood flow cooling and ultrasonic lesion formation. Med Phys. 1996;23:1287–1298
  16. Kornbluth M, Liang DH, Paloma A, Schnittger I. Native tissue harmonic imaging improves endocardial border definition and visualization of cardiac structure. J Am Soc Echocardiogr. 1998;11:693–701
  17. Kunzelman KS, Linker DT, Sai S, Miyake-Hull C, Quick D, Thomas R, et al. Acute mitral valve regurgitation created in sheep using echocardiographic guidance. J Heart Valve Dis. 1999;8:637–643
  18. Lamas GA, Mitchell GF, Flaker GC, Smith SC, Gersh BJ, Basta L, et al. Clinical significance of mitral regurgitation after acute myocardial infarction Survival and Ventricular Enlargement Investigators. Circulation. 1997;96:827–833
  19. Lee LA, Simon C, Bove EL, Mosca RS, Ebbini ES, Abrams GD, et al. High intensity focused ultrasound effect on cardiac tissues: Potential for clinical application. Echocardiography. 2000;17:563–566
  20. Lindsay BD, Chung MK, Gamache MC, Luke RA, Schechtman KB, Osborn JL, et al. Therapeutic end points for the treatment of atrioventricular node reentrant tachycardia by catheter-guided radiofrequency current. J Am Coll Cardiol. 1993;22:733–740
  21. Lizzi FL, Ketterling JA, Muratore R. Ultrasound method and system. US Patent 6,846,290. Issued January 25, 2005.
  22. Lomholt M, Nielsen SL, Hansen SB, Andersen NT, Hasenkam JM. Differential tension between secondary and primary mitral chordae in an acute in vivo porcine model. J Heart Valve Dis. 2002;11:337–345
  23. Messas E, Guerrero JL, Handschumacher MD, Conrad C, Chow CM, Sullivan S, et al. Chordal cutting: A new therapeutic approach for ischemic mitral regurgitation. Circulation. 2001;104:1958–1963
  24. Messas E, Pouzet B, Touchot B, Guerrero JL, Vlahakes GJ, Desnos M, et al. Efficacy of chordal cutting to relieve chronic persistent ischemic mitral regurgitation. Circulation. 2003;108(Suppl 1):II111–II115
  25. Muratore R. A history of the Sonocare CST-100: The first FDA-approved HIFU device. In:  Clement GT,  McDannold NJ,  Hynynen K editor. 5th International Symposium on Therapeutic Ultrasound; 2005 October 27-29; Boston, Massachusetts. Melville, NY: American Institute of Physics; 2006;p. 508–512
  26. Nielsen SL, Soerensen DD, Libergren P, Yoganathan AP, Nygaard H. Miniature C-shaped transducers for chordae tendineae force measurements. Ann Biomed Eng. 2004;32:1050–1057
  27. Oliveira DB, Dawkins KD, Kay PH, Paneth M. Chordal rupture (I: Aetiology and natural history). Br Heart J. 1983;50:312–317
  28. Otsuji Y, Handschumacher MD, Schwammenthal E, Jiang L, Song JK, Guerrero JL, et al. Insights from three-dimensional echocardiography into the mechanism of functional mitral regurgitation: Direct in vivo demonstration of altered leaflet tethering geometry. Circulation. 1997;96:1999–2008
  29. Otsuka R, Fujikura K, Hirata K, Pulerwitz T, Oe Y, Suzuki T, et al. In vitro ablation of cardiac valves using high-intensity focused ultrasound. Ultrasound Med Biol. 2005;31:109–114
  30. Otsuka R, Fujikura K, Abe Y, Okajima K, Pulerwitz T, Engel DJ, et al. Extracardiac Ablation of the Left Ventricular Septum in Beating Canine Hearts Using High-Intensity Focused Ultrasound. J Am Soc Echocardiogr. 2007;[Epub ahead of print]
  31. Rusted IE, Scheifley CH, Edwards JE. Studies of the mitral valve (I. Anatomic features of the normal mitral valve and associated structures). Circulation. 1952;6:825–831
  32. Scott-Jupp W, Barnett NL, Gallagher PJ, Monro JL, Ross JK. Ultrastructural changes in spontaneous rupture of mitral chordae tendineae. J Pathol. 1981;133:185–201
  33. Sedransk KL, Grande-Allen KJ, Vesely I. Failure mechanics of mitral valve chordae tendineae. J Heart Valve Dis. 2002;11:644–650
  34. Strickberger SA, Tokano T, Kluiwstra JU, Morady F, Cain C. Extracardiac ablation of the canine atrioventricular junction by use of high-intensity focused ultrasound. Circulation. 1999;100:203–208
  35. Susani M, Madersbacher S, Kratzik C, Vingers L, Marberger M. Morphology of tissue destruction induced by focused ultrasound. Eur Urol. 1993;23(Suppl 1):34–38
  36. Tibayan FA, Rodriguez F, Zasio MK, Bailey L, Liang D, Daughters GT, et al. Geometric distortions of the mitral valvular-ventricular complex in chronic ischemic mitral regurgitation. Circulation. 2003;108(Suppl 1):II116–II121
  37. Vykhodtseva NI, Hynynen K, Damianou C. Pulse duration and peak intensity during focused ultrasound surgery: Theoretical and experimental effects in rabbit brain in vivo. Ultrasound Med Biol. 1994;20:987–1000
  38. Weinbaum S, Jiji LM. A new simplified bioheat equation for the effect of blood flow on local average tissue temperature. J Biomech Eng. 1985;107:131–139
  39. Williamson WA, Aretz HT, Weng G, Shahian DM, Hamilton WM, Pankratov MM, et al. In vitro decalcification of aortic valve leaflets with the Er:YSGG laser, Ho:YAG laser and the Cavitron ultrasound surgical aspirator. Lasers Surg Med. 1993;13:421–428
  40. Wu F, Wang ZB, Cao YD, Chen WZ, Zou JZ, Bai J, et al. Changes in biologic characteristics of breast cancer treated with high-intensity focused ultrasound. Ultrasound Med Biol. 2003;29:1487–1492
  41. Yamamoto H, Iguro Y, Sakata R, Arata K, Yotsumoto G. Effectively treating ischemic mitral regurgitation with chordal cutting in combination with ring annuloplasty and left ventricular reshaping approach. J Thorac Cardiovasc Surg. 2005;130:589–590
  42. Yiu SF, Enriquez-Sarano M, Tribouilloy C, Seward JB, Tajik AJ. Determinants of the degree of functional mitral regurgitation in patients with systolic left ventricular dysfunction: A quantitative clinical study. Circulation. 2000;102:1400–1406

PII: S0301-5629(07)00463-2

doi: 10.1016/j.ultrasmedbio.2007.09.003

Ultrasound in Medicine and Biology
Volume 34, Issue 3 , Pages 400-405 , March 2008

Article Tools

* Image Usage & Resolution