Ultrasound in Medicine and Biology
Volume 34, Issue 3 , Pages 345-353 , March 2008

Assessment of Cerebral Autoregulation with Transcranial Doppler Sonography in Poor Bone Windows Using Constant Infusion of an Ultrasound Contrast Agent

  • Matthias W. Lorenz

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • Corresponding Author InformationAddress correspondence to: Matthias W. Lorenz, M.D., Department of Neurology, J.W. Goethe-University Frankfurt am Main, Schleusenweg 2-16, D-60528 Frankfurt/Main, Germany.
    • ,
  • Nina Thoelen

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Nadine Loesel

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Christian Lienerth

      Affiliations

    • Brain Imaging Center, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Marilen Gonzalez

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Marek Humpich

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Waltraud Roelz

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Florian Dvorak

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany
    • ,
  • Matthias Sitzer

      Affiliations

    • Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

Received 30 May 2007 ,Revised 22 July 2007 ,Accepted 4 September 2007.

References 

  1. Albrecht T, Urbank A, Mahler M, Bauer A, Dore CJ, Blomley MJ, et al. Prolongation and optimization of Doppler enhancement with a microbubble US contrast agent by using continuous infusion: preliminary experience. Radiology. 1998;207:339–347
  2. Czosnyka M, Smielewski P, Kirkpatrick P, Menon DK, Pickard JD. Monitoring of cerebral autoregulation in head-injured patients. Stroke. 1996;27:1829–1834
  3. Diehl RR, Berlit P. Funktionelle Dopplersonografie in der Neurologie. Berlin-Heidelberg: Springer-Verlag; 1996;
  4. Diehl RR, Linden D, Lucke D, Berlit P. Spontaneous blood pressure oscillations and cerebral autoregulation. Clin Auton Res. 1998;8:7–12
  5. Gosling RG, King DH. Arterial assessment by Doppler-shift ultrasound. Proc R Soc Med. 1974;67:447–449
  6. Haubrich C, Kruska W, Diehl RR, Moller-Hartmann W, Klotzsch C. Dynamic autoregulation testing in patients with middle cerebral artery stenosis. Stroke. 2003;34:1881–1885
  7. Haubrich C, Klemm A, Diehl RR, Moller-Hartmann W, Klotzsch C. M-wave analysis and passive tilt in patients with different degrees of carotid artery disease. Acta Neurol Scand. 2004;109:210–216
  8. Haubrich C, Wendt A, Diehl RR, Klotzsch C. Dynamic autoregulation testing in the posterior cerebral artery. Stroke. 2004;35:848–852
  9. Haubrich C, Kohnke A, Diehl RR, Moller-Hartmann W, Klotzsch C. Impact of vertebral artery disease on dynamic cerebral autoregulation. Acta Neurol Scand. 2005;112:309–316
  10. Hoelscher T, Schlachetzki F, Bauer A, Rosin L, Goetz B, Bogdahn U. Echo-enhanced transcranial color-coded US: Clinical usefulness of intravenous infusion versus bolus injection of SH U 508A1. Radiology. 2001;219:823–827
  11. Immink RV, van den Born BJ, van Montfrans GA, Koopmans RP, Karemaker JM, van Lieshout JJ. Impaired cerebral autoregulation in patients with malignant hypertension. Circulation. 2004;110:2241–2245
  12. Immink RV, van Montfrans GA, Stam J, Karemaker JM, Diamant M, van Lieshout JJ. Dynamic cerebral autoregulation in acute lacunar and middle cerebral artery territory ischemic stroke. Stroke. 2005;36:2595–2600
  13. Jarquin-Valdivia AA, McCartney J, Palestrant D, Johnston SC, Gress D. The thickness of the temporal squama and its implication for transcranial sonography. J Neuroimaging. 2004;14:139–142
  14. Lang EW, Diehl RR, Mehdorn HM. Cerebral autoregulation testing after aneurysmal subarachnoid hemorrhage: The phase relationship between arterial blood pressure and cerebral blood flow velocity. Crit Care Med. 2001;29:158–163
  15. Lorenz MW, Gonzalez M, Lienerth C, Loesel N, Thoelen N, Sitzer M. Influence of temporal insonation window quality on the assessment of cerebral autoregulation with transcranial Doppler sonography. Ultrasound Med Biol. 2007;33:1540–1545
  16. Marcus R, Peritz E, Gabriel KG. On closed testing procedures with special reference to ordered analysis of variance. Biometrika. 1976;63:656–660
  17. Marinoni M, Ginanneschi A, Forleo P, Amaducci L. Technical limits in transcranial Doppler recording: Inadequate acoustic windows. Ultrasound Med Biol. 1997;23:1275–1277
  18. Oehm E, Reinhard M, Keck C, Els T, Spreer J, Hetzel A. Impaired dynamic cerebral autoregulation in eclampsia. Ultrasound Obstet Gynecol. 2003;22:395–398
  19. Piechnik SK, Yang X, Czosnyka M, Smielewski P, Fletcher SH, Jones AL, et al. The continuous assessment of cerebrovascular reactivity: A validation of the method in healthy volunteers. Anesth Analg. 1999;89:944–949
  20. Postert T, Federlein J, Przuntek H, Buttner T. Insufficient and absent acoustic temporal bone window: Potential and limitations of transcranial contrast-enhanced color-coded sonography and contrast-enhanced power-based sonography. Ultrasound Med Biol. 1997;23:857–862
  21. Reinhard M, Hetzel A, Lauk M, Lucking CH. Dynamic cerebral autoregulation testing as a diagnostic tool in patients with carotid artery stenosis. Neurol Res. 2001;23:55–63
  22. Reinhard M, Muller T, Guschlbauer B, Timmer J, Hetzel A. Dynamic cerebral autoregulation and collateral flow patterns in patients with severe carotid stenosis or occlusion. Ultrasound Med Biol. 2003;29:1105–1113
  23. Reinhard M, Muller T, Guschlbauer B, Timmer J, Hetzel A. Transfer function analysis for clinical evaluation of dynamic cerebral autoregulation—A comparison between spontaneous and respiratory-induced oscillations. Physiol Meas. 2003;24:27–43
  24. Reinhard M, Muller T, Roth M, Guschlbauer B, Timmer J, Hetzel A. Bilateral severe carotid artery stenosis or occlusion—Cerebral autoregulation dynamics and collateral flow patterns. Acta Neurochir (Wien). 2003;145:1053–1060
  25. Reinhard M, Roth M, Muller T, Czosnyka M, Timmer J, Hetzel A. Cerebral autoregulation in carotid artery occlusive disease assessed from spontaneous blood pressure fluctuations by the correlation coefficient index. Stroke. 2003;34:2138–2144
  26. Rohrberg M, Brodhun R. Measurement of vasomotor reserve in the transcranial Doppler-CO(2) test using an ultrasound contrast agent (Levovist). Stroke. 2001;32:1298–1303
  27. White RP, Markus HS. Impaired dynamic cerebral autoregulation in carotid artery stenosis. Stroke. 1997;28:1340–1344
  28. Zhang R, Zuckerman JH, Giller CA, Levine BD. Transfer function analysis of dynamic cerebral autoregulation in humans. Am J Physiol. 1998;274:H233–H241

PII: S0301-5629(07)00438-3

doi: 10.1016/j.ultrasmedbio.2007.09.001

Ultrasound in Medicine and Biology
Volume 34, Issue 3 , Pages 345-353 , March 2008

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