Ultrasound in Medicine and Biology
Volume 33, Issue 11 , Pages 1706-1719 , November 2007

In Vivo Assessment of Myocardial Stiffness with Acoustic Radiation Force Impulse Imaging

  • Stephen J. Hsu

      Affiliations

    • Department of Biomedical Engineering, Duke University, Durham, NC, USA
    • Corresponding Author InformationAddress correspondence to: Stephen J. Hsu, Mail: BME Dept., Duke University, 136, Hudson Hall, Durham, NC 27708, USA.
    • ,
  • Richard R. Bouchard

      Affiliations

    • Department of Biomedical Engineering, Duke University, Durham, NC, USA
    • ,
  • Douglas M. Dumont

      Affiliations

    • Department of Biomedical Engineering, Duke University, Durham, NC, USA
    • ,
  • Patrick D. Wolf

      Affiliations

    • Department of Biomedical Engineering, Duke University, Durham, NC, USA
    • ,
  • Gregg E. Trahey

      Affiliations

    • Department of Biomedical Engineering, Duke University, Durham, NC, USA
    • Department of Radiology, Duke University Medical Center, Durham, NC, USA

References 

  1. Amundsen BH, Helle-Valle T, Edvardsen T, Torp H, Crosby J, Lyseggen E, et al. Noninvasive myocardial strain mea-surement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging. J Am Coll Cardiol. 2006;47(4):789–793
  2. Baldwin SL, Marutyan KR, Yang M, Wallace KD, Holland MR, Miller JG. Measurements of the anisotropy of ultrasonic attenuation in freshly excised myocardium. J Acoust Soc Am. 2006;119(5 Pt 1):3130–3139
  3. Bercoff J, Chaffai S, Tanter M, Fink M. Ultrafast imaging of beamformed shear waves induced by the acoustic ratiaion foce in soft tissues: Application to transient elastography. 2002;Proceedings of the 2002 IEEE Ultrasonics Symposium
  4. Borbély A, van der Velden J, Papp Z, Bronzwaer JG, Edes I, Stienen GJ, et al. Cardiomyocyte stiffness in diastolic heart failure. Circulation. 2005;111(6):774–781
  5. Cingolani OH, Yang XP, Cavasin MA, Carretero OA. Increased systolic performance with diastolic dysfunction in adult spontaneously hypertensive rats. Hypertension. 2003;41(2):249–254
  6. Dahl JJ, Pinton GF, Palmeri ML, Agrawal V, Nightingale KR, Trahey GE. A parallel tracking method for acoustic radiation force impulse imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2007;54(2):301–312
  7. D’hooge J, Konofagou E, Jamal F, Heimdal A, Barrios L, Bijnens B, et al. Two-dimensional ultrasonic strain rate measurement of the human heart in vivo. IEEE Trans Ultrason Ferroelectr Freq Control. 2002;49(2):281–286
  8. Fahey B, Nightingale K, Nelson R, Palmeri M, Trahey G. Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility. Ultrasound Med Biol. 2005;31(9):1185–1198
  9. Fahey B, Nightingale K, Stutz D, Trahey G. Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: Preliminary ex vivo results. Ultrasound in Medicine and Biology. 2004;30(3):321–328
  10. Fahey B, Nightingale K, Wolf P, Trahey G. Acoustic radiation force impulse imaging of myocardial radiofrequency ablation: Initial in vivo results. IEEE Transactions on Ultrasonics, Ferroelectronics and Frequency Control. 2005;52(4):631–641
  11. Fahey BJ, Palmeri ML, Trahey GE. Frame rate considerations for abdominal acoustic radiation force impulse imaging. Ultrasonic Imaging. 2006;28(4):193–210
  12. Garot J, Derumeaux GA, Monin JL, Duval-Moulin AM, Simon M, Pascal D, et al. Quantitative systolic and diastolic transmyocardial velocity gradients assessed by m-mode colour doppler tissue imaging as reliable indicators of regional left ventricular function after acute myocardial infarction. Eur Heart J. 1999;20(8):593–603
  13. Gerber BL, Garot J, Bluemke DA, Wu KC, Lima JA. Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction. Circulation. 2002;106(9):1083–1089
  14. Haws C, Lux R. Correlation between in vivo transmembrane action potential durations and activation-recovery intervals from electrograms (effects of interventions that alter repolarization time). Circulation. 1990;81(1):281–288
  15. Heimdal A, Stoylen A, Torp H, Skjaerpe T. Real-time strain rate imaging of the left ventricle by ultrasound. J Am Soc Echocardiogr. 1998;11(11):1013–1019
  16. Herbots L, Maes F, D’hooge J, Claus P, Dymarkowski S, Mertens P, et al. Quantifying myocardial deformation throughout the cardiac cycle: a comparison of ultrasound strain rate, grey-scale m-mode and magnetic resonance imaging. Ultrasound Med Biol. 2004;30(5):591–598
  17. Hsu SJ, Fahey BJ, Dumont DM, Wolf PD, Trahey GE. Challenges and implementation of radiation force imaging with an intra-cardiac ultrasound transducer. IEEE Transactions on Ultrasonics, Ferroelectronics and Frequency Control. 2007;54(5):996–1009
  18. Jalil JE, Doering CW, Janicki JS, Pick R, Shroff SG, Weber KT. Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. Circ Res. 1989;64(6):1041–1050
  19. Jegger D, Mallik AS, Nasratullah M, Jeanrenaud X, da Silva R, Tevaearai H, et al. The effect of a myocardial infarction on the normalized time-varying elastance curve. J Appl Physiol. 2006;
  20. Kasai C, Namekawa K. Real-time two-dimensional blood flow imaging using an autocorrelation technique. IEEE Transactions on Ultrasonics, Ferroelectronics and Frequency Control. 1985;32:458–463
  21. Kawaguchi M, Hay I, Fetics B, Kass D. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: Implications for systolic and diastolic reserve limiations. Circulation. 2003;107:714–720
  22. Kheradvar A, Milano M, Gorman R, Gorman J, Gharib M. Assessment of left ventricular viscoelastic components based on ventricular harmonic behavior. Cardiovascular Engineering: An International Journal. 2006;6(1):31–39
  23. Klein C, Nekolla SG, Bengel FM, Momose M, Sammer A, Haas F, et al. Assessment of myocardial viability with contrast-enhanced magnetic resonance imaging: comparison with positron emission tomography. Circulation. 2002;105(2):162–167
  24. Konofagou E, D’hooge J, Ophir J. Myocardial elastography-a feasibility study in vivo. Ultrasound Med Biol. 2002;28(4):475–482
  25. Koyama Y, Mochizuki TJH. Computed tomography assessment of myocardial perfusion, viability, and function. Journal of Magnetic Resonance Imaging. 2004;19:800–815
  26. Langeland S, D’hooge J, Claessens T, Claus P, Verdonck P, Suetens P, et al. Rf-based two-dimensional cardiac strain estimation: a validation study in a tissue-mimicking phantom. IEEE Trans Ultrason Ferroelectr Freq Control. 2004;51(11):1537–1546
  27. Lardo AC, McVeigh ER, Jumrussirikul P, Berger RD, Calkins H, Lima J, et al. Visualization and temporal/spatial characterization of cardiac radiofrequency ablation lesions using magnetic resonance imaging. Circulation. 2000;102(6):698–705
  28. Lyseggen E, Skulstad H, Helle-Valle T, Vartdal T, Urheim S, Rabben SI, et al. Myocardial strain analysis in acute coronary occlusion: a tool to assess myocardial viability and reperfusion. Circulation. 2005;112(25):3901–3910
  29. McVeigh ER. MRI of myocardial function: motion tracking techniques. Magn Reson Imaging. 1996;14(2):137–150
  30. Micari A, Pascotto M, Jayaweera AR, Sklenar J, Goodman NC, Kaul S. Cyclic variation in ultrasonic myocardial integrated backscatter is due to phasic changes in the number of patent myocardial microvessels. J Ultrasound Med. 2006;25(8):1009–1019
  31. Mirsky I, Tajimi T. The development of the entire end systolic pressure-volume and ejection fraction-afterload relations: a new concept of systolic myocardial stiffness. KLP Circ Res. 1987;76:343–356
  32. Nakano K, Sugawara M, Ishihara K, Kanazawa S, Corin WJ, Denslow S, et al. Myocardial stiffness derived from end-systolic wall stress and logarithm of reciprocal of wall thickness (contractility index independent of ventricular size). Circulation. 1990;82(4):1352–1361
  33. Nightingale K, Bentley R, Trahey G. Observations of tissue response to acoustic radiation force: Opportunities for imaging. Ultrasonic Imaging. 2002;24:100–108
  34. Nightingale K, Nightingale R, Stutz D, Trahey G. Acoustic radiation force impulse imaging of in vivo vastus medialis muscle under varying isometric load. Ultrasonic Imaging. 2002;24:100–108
  35. Nightingale K, Palmeri M, Nightingale R, Trahey G. On the feasibility of remote palpation using acoustic radiation force. J Acoust Soc Am. 2001;110(1):625–634
  36. Nightingale K, Soo M, Nightingale R, Trahey G. Acoustic radiation force impulse imaging: In vivo demonstration of clinical feasibility. Ultrasound in Medicine and Biology. 2002;28(2):227–235
  37. Nyborg W. Acoustic streaming. In:  Mason W editors. Physical Acoustics. vol. IIB:New York: Academic Press Inc; 1965;p. 265–331chap. 11
  38. O’Brien PD, O’Brien WD, Rhyne TL, Warltier DC, Sagar KB. Relation of ultrasonic backscatter and acoustic propagation properties to myofibrillar length and myocardial thickness. Circulation. 1995;91(1):171–175
  39. Oliphant T, Manduca R, Ehman A, Greenleaf J. Complex-valued stiffness reconstruction from magnetic resonance elastography by algebraic inversion of the differential equation. Magnetic Resonance in Medicine. 2000;
  40. Palmeri ML, Nightingale KR. On the thermal effects associated with radiation force imaging of soft tissue. IEEE Trans. Ultrason Ferroelec Freq. Contr. 2004;51:551–565
  41. Palmeri M, S.A. M, Trahey G, Nightingale K. Ultrasonic tracking of acoustic radiation force-induced displacements in homogeneous media. IEEE-UFFC in press.
  42. Pinton G, Dahl J, Trahey G. Rapid tracking of small displacments with ultrasound. IEEE Transactions on Ultrasonics, Ferroelectronics and Frequency Control. 2006;53(6):1103–1117
  43. Pislaru C, Bruce CJ, Anagnostopoulos PC, Allen JL, Seward JB, Pellikka PA, et al. Ultrasound strain imaging of altered myocardial stiffness: stunned versus infarcted reperfused myocardium. Circulation. 2004;109(23):2905–2910
  44. Sandrin L, Tanter M, Catheline S, Fink M. Shear modulus imaging with 2-D transient elastography. IEEE Transactions on Ultrasonics, Ferroelectronics and Frequency Control. 2002;426–435
  45. Sharma A, Soo M, Trahey G, Nightingale K. Acoustic radiation force impulse imaging of in vivo breast masses. Proceedings of the 2004 IEEE Ultrasonics Symposium. 2004;1:728–731
  46. Torr G. The acoustic radiation force. American Journal of Physics. 1984;52:402–408
  47. Wen H, Bennett E, Epstein N, Plehn J. Magnetic resonance imaging assessment of myocardial elastic modulus and viscosity using displacement imaging and phase-contrast velocity mapping. Magnetic Resonance in Medicine. 2005;54:538–548
  48. Wickline SA, Thomas LJ, Miller JG, Sobel BE, Perez JE. A relationship between ultrasonic integrated backscatter and myocardial contractile function. J Clin Invest. 1985;76(6):2151–2160
  49. Yu EH, Skyba DM, Leong-Poi H, Sloggett C, Jamorski M, Garg R, et al. Incremental value of parametric quantitative assessment of myocardial perfusion by triggered low-power myocardial contrast echocardiography. J Am Coll Cardiol. 2004;43(10):1807–1813
  50. Zile MR, Baicu CF, Gaasch WH. Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med. 2004;350(19):1953–1959

PII: S0301-5629(07)00253-0

doi: 10.1016/j.ultrasmedbio.2007.05.009

Ultrasound in Medicine and Biology
Volume 33, Issue 11 , Pages 1706-1719 , November 2007

Article Tools

* Image Usage & Resolution