Ultrasound in Medicine and Biology
Volume 33, Issue 8 , Pages 1244-1250 , August 2007

Comparison of Sonographic Appearance of Normal and Postradiotherapy Parotid Glands: A Preliminary Study

  • Michael Ying

      Affiliations

    • Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China
    • Corresponding Author InformationAddress correspondence to: Dr. Michael Ying, Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.
    • ,
  • Vincent W.C. Wu

      Affiliations

    • Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China
    • ,
  • Dora L.W. Kwong

      Affiliations

    • Department of Clinical Oncology, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China

Received 16 December 2006 ,Revised 5 February 2007 ,Accepted 25 February 2007.

References 

  1. Bude RO, Rubin JM, Adler RS. Power versus conventional color Doppler sonography: Comparison in the depiction of normal intrarenal vasculature. Radiology. 1994;192:777–780
  2. Chambers MS, Garden AS, Kies MS, Martin JW. Radiation-induced xerostomia in patients with head and neck cancer: Pathogenesis, impact on quality of life, and management. Head Neck. 2004;26:796–807
  3. Choi MY, Lee JW, Jang KJ. Distinction between benign and malignant causes of cervical, axillary, and inguinal lymphadenopathy: Value of Doppler spectral waveform analysis. Am J Roentgenol. 1995;165:981–984
  4. Cosgrove DO, Kedar RP, Bamber JC, et al. Breast diseases: Color Doppler US in differential diagnosis. Radiology. 1993;189:99–104
  5. Criswell MA, Sinha CK. Hyperthermic, supersaturated humidification in the treatment of xerostomia. Laryngoscope. 2001;111:992–996
  6. Deng X, Marinov G, Marois Y, Guidoin R. Mechanical characteristics of the canine thoracic duct: What are the driving forces of the lymph flow?. Biorheology. 1999;36:391–399
  7. Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys. 1991;21:109–122
  8. Evans RM, Ying M, Ahuja AT. Ultrasound. In:  Ahuja AT,  Evans RM,  King AD,  van Hasselt CA editor. Imaging in head and neck cancer. A practical approach. London: Greenwich Medical Media Limited; 2003;p. 3–16
  9. Grehn AL, Gustafsson H, Franzen L, Thornell LE, Henriksson R. Ultrastructural morphometry of parotid acinar cells following fractionated irradiation. Oral Oncol. 1997;33:23–28
  10. Grotz KA, Wustenberg P, Kohnen R, et al. Prophylaxis of radiogenic sialadenitis and mucositis by coumarin/troxerutine in patients with head and neck cancer—a prospective, randomized, placebo-controlled, double-blind study. Br J Oral Maxillofac Surg. 2001;39:34–39
  11. Hockerfelt U, Kjorell U, Malm V, et al. VIP in the rat parotid gland in response to irradiation. Regul Pept. 1997;68:83–89
  12. Howlett DC. High resolution ultrasound assessment of the parotid gland. Br J Radiol. 2003;76:271–277
  13. Kelly IM, Lees WR, Watts RW. Case report: Grey-scale and colour Doppler ultrasound appearance of acute sarcoidosis of the parotid gland. Clin Radiol. 1994;49:425–426
  14. Konings AW, Faber H, Cotteleer F, Vissink A, Coppes RP. Secondary radiation damage as the main cause for unexpected volume effects: A histopathologic study of the parotid gland. Int J Radiat Oncol Biol Phys. 2006;64:98–105
  15. Kwong DL, Sham JS, Au GK, et al. Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: A factorial study. J Clin Oncol. 2004;22:2643–2653
  16. Leek H, Albertsson M. Pilocarpine treatment of xerostomia in head and neck patients. Micron. 2002;33:153–155
  17. Mandel L. Ultrasound findings in HIV-positive patients with parotid gland swellings. J Oral Maxillofac Surg. 2001;59:283–286
  18. McNicholas MM, Mercer PM, Miller JC, et al. Color Doppler sonography in the evaluation of palpable breast masses. Am J Roentgenol. 1993;161:765–771
  19. Nagler RM. The enigmatic mechanism of irradiation-induced damage to the major salivary glands. Oral Dis. 2002;8:141–146
  20. Nagler RM, Baum BJ, Fox PC. Effects of X irradiation on the function of rat salivary glands at 3 and 40 days. Radiat Res. 1993;136:392–396
  21. Nomayr A, Lell M, Sweeney R, Bautz W, Lukas P. MRI appearance of radiation-induced changes of normal cervical tissues. Eur Radiol. 2001;11:1807–1817
  22. Pow EH, Kwong DL, McMillan AS, et al. Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: Initial report on a randomized controlled clinical trial. Int J Radiat Oncol Biol Phys. 2006;66:981–991
  23. Price RE, Ang KK, Stephens LC, Peters LJ. Effects of continuous hyperfractionated accelerated and conventionally fractionated radiotherapy on the parotid and submandibular salivary glands of rhesus monkeys. Radiother Oncol. 1995;34:39–46
  24. Radfar L, Sirois DA. Structural and functional injury in minipig salivary glands following fractionated exposure to 70 Gy of ionizing radiation: An animal model for human radiation-induced salivary gland injury. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96:267–274
  25. Seifert G. Etiology and differential diagnosis of sialadenitis. Laryngorhinootologie. 1995;74:274–281
  26. Shimizu M, Okamura K, Yoshiura K, et al. Sonographic diagnostic criteria for screening Sjogren’s syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:85–93
  27. Steinkamp HJ, Maurer J, Cornehl M, et al. Recurrent cervical lymphadenopathy: Differential diagnosis with color- duplex sonography. Eur Arch Otorhinolaryngol. 1994;251:404–409
  28. Stephens LC, Schultheiss TE, Price RE, Ang KK, Peters LJ. Radiation apoptosis of serous acinar cells of salivary and lacrimal glands. Cancer. 1991;67:1539–1543
  29. Stern MH, Turner JE, Jett LS, Mincer H, McGinnis . Electron microscopic changes in rat parotid and submandibular glands subsequent total body irradiation with fast neutrons. Oral Surg Oral Med Oral Pathol. 1976;42:620–630
  30. Teymoortash A, Simolka N, Schrader C, Tiemann M, Werner JA. Lymphocyte subsets in irradiation-induced sialadenitis of the submandibular gland. Histopathology. 2005;47:493–500
  31. Ying M, Ahuja A, Brook F. Accuracy of sonographic vascular features in differentiating different causes of cervical lymphadenopathy. Ultrasound Med Biol. 2004;30:441–447
  32. Ying M, Ahuja AT, Yuen HY. Grey-scale and power Doppler sonography of unusual cervical lymphadenopathy. Ultrasound Med Biol. 2004;30:449–454
  33. Ying MTC. In: Power Doppler sonography of normal and abnormal cervical lymph nodes, in PhD Thesis, Department of Optometry and Radiography. Hong Kong: The Hong Kong Polytechnic University; 2002;p. 236

PII: S0301-5629(07)00109-3

doi: 10.1016/j.ultrasmedbio.2007.02.016

Ultrasound in Medicine and Biology
Volume 33, Issue 8 , Pages 1244-1250 , August 2007

Article Tools

* Image Usage & Resolution