Ultrasound in Medicine and Biology
Volume 33, Issue 3 , Pages 362-370 , March 2007

Vasodilation of Epicardial Coronary Artery can be Measured with Transthoracic Echocardiography

  • Tuomas O. Kiviniemi

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • Corresponding Author InformationAddress correspondence to: Tuomas Kiviniemi, Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4-8, FIN-20520 Turku, Finland.
    • ,
  • Jyri O. Toikka

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland
    • ,
  • Juha W. Koskenvuo

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • ,
  • Antti Saraste

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • Department of Medicine, Turku University Hospital, Turku, Finland
    • ,
  • Markku Saraste

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • ,
  • Jussi P. Pärkkä

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • ,
  • Olli T. Raitakari

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    • ,
  • Jaakko J. Hartiala

      Affiliations

    • Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland

Received 6 March 2006 ,Revised 8 August 2006 ,Accepted 17 August 2006.

References 

  1. Antony I, Aptecar E, Lerebours G, Nitenberg A. Coronary artery constriction caused by the cold pressor test in human hypertension. Hypertension. 1994;24:212–219
  2. Baumgart D, Haude M, Liu F, Ge J, Goerge G, Erbel R. Current concepts of coronary flow reserve for clinical decision making during cardiac catheterization. Am Heart J. 1998;136:136–149
  3. Benvenuti C, Aptecar E, Mazzucotelli JP, Jouannot P, Loisance D, Nitenberg A. Coronary-artery response to cold-pressor test is impaired early after operation in heart-transplant recipients. J Am Coll Cardiol. 1995;26:446–451
  4. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–310
  5. Caiati C, Montaldo C, Zedda N, Bina A, Iliceto S. New noninvasive method for coronary flow reserve assessment: Contrast-enhanced transthoracic second harmonic echo Doppler. Circulation. 1999;99:771–778
  6. Caiati C, Montaldo C, Zedda N, et al. Validation of a new noninvasive method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve: Comparison with intracoronary Doppler flow wire. J Am Coll Cardiol. 1999;34:1193–1200
  7. Chandraratna PA, Nimalasuriya AR, Vlachonassios KD, et al. Usefulness of the response of flow velocity in the left anterior descending coronary artery to the cold pressor test for evaluating endothelium-dependent vascular relaxation in the coronary microvasculature by transesophageal echocardiography in subjects with angiographically normal coronary arteries. Am J Cardiol. 1999;84:1362–1365A8
  8. Chaudhry FA, Ren JF, Ramani K, et al. Validation of transesophageal echocardiography to determine physiologic coronary flow. Echocardiograph Am J Cardiovasc Ultrasound Allied Technique. 2001;18:553–557
  9. Clarke GD, Eckels R, Chaney C, et al. Measurement of absolute epicardial coronary artery flow and flow reserve with breath-hold cine phase-contrast magnetic resonance imaging. Circulation. 1995;91:2627–2634
  10. Deng YB, Wang XF, Li CL. A new noninvasive method for evaluation of coronary endothelial function in hypertensive patients based on change in diameter of the left main coronary artery induced by cold pressor test using echocardiography. Clin Cardiol. 2001;24:291–296
  11. Dimitrow PP, Krzanowski M, Nizankowski R, Szczeklik A, Dubiel JS. Comparison of the effect of verapamil and propranolol on response of coronary vasomotion to cold pressor test in symptomatic patients with hypertrophic cardiomyopathy. Cardiovasc Drugs Ther. 2000;14:643–650
  12. Doucette JW, Corl PD, Payne HM, et al. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation. 1992;85:1899–1911
  13. Faletra F, Cipriani M, Dechiara F, et al. Imaging the left anterior descending coronary-artery by high-frequency transthoracic echocardiography in heart-transplant patients. Am J Cardiol. 1995;75:855–858
  14. Gradus-Pizlo I, Bigelow B, Mahomed Y, Sawada SG, Rieger K, Feigenbaum H. Left anterior descending coronary artery wall thickness measured by high-frequency transthoracic and epicardial echocardiography includes adventitia. Am J Cardiol. 2003;91:27–32
  15. Gradus-Pizlo I, Sawada SG, Wright D, Segar DS, Feigenbaum H. Detection of subclinical coronary atherosclerosis using two-dimensional, high-resolution transthoracic echocardiography. J Am Coll Cardiol. 2001;37:1422–1429
  16. Hildick-Smith DJ, Johnson PJ, Wisbey CR, Winter EM, Shapiro LM. Coronary flow reserve is supranormal in endurance athletes: An adenosine transthoracic echocardiographic study. Heart. 2000;84:383–389
  17. Hildick-Smith DJ, Maryan R, Shapiro LM. Assessment of coronary flow reserve by adenosine transthoracic echocardiography: Validation with intracoronary Doppler. J Am Soc Echocardiogr. 2002;15:984–990
  18. Hildick-Smith DJ, Shapiro LM. Transthoracic echocardiographic measurement of coronary artery diameter: Validation against quantitative coronary angiography. J Am Soc Echocardiogr. 1998;11:893–897
  19. Hildick-Smith DJ, Shapiro LM. Potential use of transthoracic echocardiography in the assessment of coronary flow reserve. J Am Soc Echocardiogr. 1999;12:590–595
  20. Hozumi T, Yoshida K, Akasaka T, et al. Noninvasive assessment of coronary flow velocity and coronary flow velocity reserve in the left anterior descending coronary artery by Doppler echocardiography: Comparison with invasive technique. J Am Coll Cardiol. 1998;32:1251–1259
  21. Hozumi T, Yoshida K, Ogata Y, et al. Noninvasive assessment of significant left anterior descending coronary artery stenosis by coronary flow velocity reserve with transthoracic color Doppler echocardiography. Circulation. 1998;97:1557–1562
  22. Kiviniemi TO, Saraste M, Koskenvuo JW, et al. Coronary artery diameter can be assessed reliably with transthoracic echocardiography. Am J Physiol Heart Circ Physiol. 2004;286:H1515–H1520
  23. Koskenvuo JW, Saraste M, Niemi P, et al. Correlation of transthoracic Doppler echocardiography and magnetic resonance imaging in measuring left anterior descending artery flow velocity and time-course of dipyridamole-induced coronary flow increase. Scand J Clin Lab Invest. 2003;63:65–72
  24. Macho P, Hintze TH, Vatner SF. Regulation of large coronary-arteries by increases in myocardial metabolic demands in conscious dogs. Circ Res. 1981;49:594–599
  25. Marcus JT, Smeenk HG, Kuijer JPA. Flow profiles in the left anterior descending and the right coronary artery assessed by MR velocity quantification: Effects of through-plane and in-plane motion of the heart. J Comput Assist Tomogr. 1999;23:567–576
  26. Nabel EG, Ganz P, Gordon JB, Alexander RW, Selwyn AP. Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test. Circulation. 1988;77:43–52
  27. Nitenberg A, Antony I, Aptecar E, Arnoult F, Lerebours G. Impairment of flow-dependent coronary dilation in hypertensive patients (Demonstration by cold pressor test induced flow velocity increase). Am J Hypertens. 1995;8:13S–18S
  28. Nitenberg A, Ledoux S, Valensi P, Sachs R, Attali JR, Antony I. Impairment of coronary microvascular dilation in response to cold pressor–induced sympathetic stimulation in type 2 diabetic patients with abnormal stress thallium imaging. Diabetes. 2001;50:1180–1185
  29. Nitenberg A, Valensi P, Sachs R, Cosson E, Attali JR, Antony I. Prognostic value of epicardial coronary artery constriction to the cold pressor test in type 2 diabetic patients with angiographically normal coronary arteries and no other major coronary risk factors. Diabetes Care. 2004;27:208–215
  30. Oskarsson G, Pesonen E. Flow dynamics in the left anterior descending coronary artery in infants with idiopathic dilated cardiomyopathy. Am J Cardiol. 2002;90:557–561
  31. Petrovic O, Elsner GB, Wilensky RL, Swanson ST, Feigenbaum H. Transthoracic echocardiographic detection of coronary atherosclerosis. Am J Cardiol. 1996;77:569–574
  32. Pitkänen OP, Nuutila P, Raitakari OT, et al. Coronary flow reserve in young men with familial combined hyperlipidemia. Circulation. 1999;99:1678–1684
  33. Pitkänen OP, Nuutila P, Raitakari OT, et al. Coronary flow reserve is reduced in young men with IDDM. Diabetes. 1998;47:248–254
  34. Pitkänen OP, Raitakari OT, Niinikoski H, et al. Coronary flow reserve is impaired in young men with familial hypercholesterolemia. J Am Coll Cardiol. 1996;28:1705–1711
  35. Presti CF, Feigenbaum H, Armstrong WF, Ryan T, Dillon JC. Digital two-dimensional echocardiographic imaging of the proximal left anterior descending coronary-artery. Am J Cardiol. 1987;60:1254–1259
  36. Ross JJ, Mintz GS, Chandrasekaran K. Transthoracic 2-dimensional high-frequency (7.5 MHz) ultrasonic visualization of the distal left anterior descending coronary-artery. J Am Coll Cardiol. 1990;15:373–377
  37. Saraste M, Koskenvuo JW, Knuuti J, et al. Coronary flow reserve: Measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography. Clin Physiol. 2001;21:114–122
  38. Saraste M, Koskenvuo JW, Mikkola J, Pelttari L, Toikka JO, Hartiala JJ. Technical achievement: Transthoracic Doppler echocardiography can be used to detect LAD restenosis after coronary angioplasty. Clin Physiol. 2000;20:428–433
  39. Schindler TH, Hornig B, Buser PT, et al. Prognostic value of abnormal vasoreactivity of epicardial coronary arteries to sympathetic stimulation in patients with normal coronary angiograms. Arterioscler Thromb Vasc Biol. 2003;23:495–501
  40. Snapir A, Koskenvuo J, Toikka J, et al. Effects of common polymorphisms in the alpha1A-, alpha2B-, beta1- and beta2-adrenoreceptors on haemodynamic responses to adrenaline. Clin Sci. 2003;104:509–520(Lond)
  41. Vered Z, Katz M, Rath S, et al. Two-dimensional echocardiographic analysis of proximal left main coronary-artery in humans. Am Heart J. 1986;112:972–976
  42. Weyman AE, Feigenbaum H, Dillon JC, Johnston KW, Eggleton RC. Noninvasive visualization of left main coronary-artery by cross-sectional echocardiography. Circulation. 1976;54:169–174
  43. Yasuoka K, Harada K, Tamura M, Toyono M, Takada G. Blood flow in the left anterior descending coronary artery in children with ventricular septal defect. J Am Soc Echocardiogr. 2002;15:807–813
  44. Zeiher AM, Drexler H, Wollschlaeger H, Saurbier B, Just H. Coronary vasomotion in response to sympathetic-stimulation in humans—Importance of the functional integrity of the endothelium. J Am Coll Cardiol. 1989;14:1181–1190
  45. Zeiher AM, Drexler H, Wollschlager H, Just H. Modulation of coronary vasomotor tone in humans—Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation. 1991;83:391–401

PII: S0301-5629(06)01807-2

doi: 10.1016/j.ultrasmedbio.2006.08.012

Ultrasound in Medicine and Biology
Volume 33, Issue 3 , Pages 362-370 , March 2007

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