Superficial soft-tissue lymphoma: Sonographic appearance and early survival

Chiou, Hong-Jen; Chou, Yi-Hong; Chiou, See-Ying; Chen, Wei-Ming; Chen, Winby; Wan, Hsing-Kai; Chao, Ta-Chung; Chang, Cheng-Yen

doi:10.1016/j.ultrasmedbio.2006.05.011

« Previous Next »Ultrasound in Medicine and Biology
Volume 32, Issue 9 , Pages 1287-1297, September 2006

Superficial soft-tissue lymphoma: Sonographic appearance and early survival

Hong-Jen Chiou
- Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
- Address correspondence to: Hong-Jen Chiou, MD, Department of Radiology, Taipei Veterans General Hospital, No.201, Sec.2, Shih-Pai Rd, Taipei, 11217, Taiwan.
Yi-Hong Chou
- Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
See-Ying Chiou
- Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
Wei-Ming Chen
- Department of Orthopedic Surgery, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
Winby Chen
- Department of Pathology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
Hsing-Kai Wan
- Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
Ta-Chung Chao
- Department of Oncology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
Cheng-Yen Chang
- Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan

Received 7 March 2006; received in revised form 26 April 2006; accepted 11 May 2006.

Abstract

We evaluated superficial soft-tissue lymphomas on high-resolution ultrasonography (HRUS) in 43 patients (17 women, 26 men; mean, 59.7 y; range, 12 to 90 y), with 1- to 97-month follow-up. Clinical presentations, tumor location and morphology, echogenicity on HRUS and color-encoding grades on Doppler ultrasonography (CDUS) were assessed. Clinical presentations did not significantly differ with tumor location or morphology. Types of lymphoma did not significantly differ in echogenicity, although most were hypoechogenic. On CDUS, most lymphomas were hypervascular, but grades did not significantly depend on the type of tumor. On Kaplan–Meier analysis with log-rank testing, survival did not differ by age (divided at 65 y), sex, tumor location or size (cut-off, 5 cm), CDUS grade or pathology. Survival was significantly related to clinical presentation (p < 0.0095) and tumor morphology (p < 0.0354). HRUS and CDUS were good modalities to detect the masses and provided important pretreatment information. (E-mail: hjchiou@vghtpe.gov.tw)

Key Words: Lymphoma , Soft tissue , Ultrasound