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Volume 36, Issue 1, Pages 86-94 (January 2010)


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Time Reversal Acoustic Focusing With A Catheter Balloon

Yegor D. SinelnikovCorresponding Author Informationemail address, Alexander M. Sutin, Andrey Y. Vedernikov, Armen P. Sarvazyan

Received 1 December 2008; received in revised form 22 June 2009; accepted 5 August 2009. published online 09 November 2009.

Abstract 

The ability to deliver configurable myocardial lesions was noted as a critical factor to the success of atrial fibrillation (AF) treatment. This article considers the implementation of time reversal acoustics (TRA) principles for ultrasound focusing using an AF cardiac catheter developed for pulmonary vein isolation. Experiments conducted with a single transmitting channel demonstrated that a catheter balloon could be used as an acoustic reverberator to enable focusing and steering of ultrasound short pulses in the TRA mode. The spatial effectiveness of the TRA focusing was improved using a catheter balloon of irregular, asymmetric shape and using a binary mode of ultrasound radiation. The experiments demonstrated the ability of steering the focal point over several millimeters without degradation of the focusing quality. An ability of the TRA mode to produce suitable therapeutic application focusing of long continuous ultrasonic signals was characterized in a theoretical model. (E-mail: yegorasha@yahoo.com)

 ProRhythm, Inc., Ronkonkoma, NY, USA

 Artann Laboratories, West Trenton, NJ, USA

 Siemens Healthcare Sector, Moscow, Russia

Corresponding Author InformationAddress correspondence to: Yegor Sinelnikov, ProRhythm Inc., 105 Comac Street, Ronkonkoma, NY 11779.

PII: S0301-5629(09)01442-2

doi:10.1016/j.ultrasmedbio.2009.08.004


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